Figure 1 - full size

 

Figure 1.
Representative parts of the PDSD spectra of fully labeled ZnMMP-12 (orange), fully labeled CoMMP-12 (purple), diluted CoMMP-12 (green), and diluted ZnMMP-12 (cyan). (A and C) The peaks of Val-217, which is affected only by intramolecular pcs, and thus the shifts observed in full-labeled samples are analogous to those observed in diluted samples. (B and D) The peaks of Thr-154, which is strongly affected only by intermolecular pcs, and the shifts observed in fully-labeled samples differ from those observed in diluted samples by the intermolecular contributions.