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Figure 1.
Crystal structure of WDR5 in complex with the MLL1 Win
peptide. a, surface representation of WDR5 (magenta) showing the
location of MLL1 Win peptide (yellow) bound to the smaller
opening at the top of WDR5. b, cutaway view of WDR5 in complex
with MLL1 Win peptide showing the location of the 3[10]-helix
(yellow ribbon) and the insertion of the Arg-3765 side chain
into the central tunnel.
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