Figure 1 - full size

 

Figure 1.
Figure 1. Ribbon Diagram of the ICAM-5/dm-I Complex
Two symmetry-related complexes of the ICAM-5/dm-I domain are shown. In one complex ICAM-5 is in cyan and the I domain in green. In the other complex the I domain is in magenta and the ICAM-5 molecule is in shadow for clarity. The C-terminal α7 helix of the magenta I domain inserts into a groove in the green I domain in an upside-down fashion. Glu-37 in ICAM-5 D1 that binds to the I domain's MIDAS is shown in red as a ball-and-stick model. The figures are all prepared with Pymol (http://www.pymol.org/).

The above figure is reprinted from an Open Access publication published by Cell Press: Mol Cell (2008, 31, 432-437) copyright 2008.