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Figure 1.
Fig. 1. Structure of cpSRP43. (A) Scheme of the domain
structure of cpSRP43 with chromodomains (CD1 to 3) and ankyrin
repeats (Ank1 to 4). Domains present in the crystal structure
are given by residue numbers and are indicated in rainbow
colors. (B) Side view of cpSRP43 in ribbon representation. The
domains are labeled. (C) Side view of cpSRP43 [90° rotation
with respect to (B)]. Secondary structure elements are numbered.
The N- and C-termini are labeled. (D) Front view of cpSRP43. The
surface representation shows two hydrophobic grooves separated
by a positive ridge. The molecular surface is colored blue and
red according to positive and negative electrostatic potential,
respectively. The asterisk highlights Tyr^204 in Ank3. (E) Back
view of cpSRP43 [same view as in (C)] showing the highly
negatively charged surface with a spacing of negative charges
reminiscent of RNA (see fig. S2).
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