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Figure 1.
Stereo ribbon diagrams of the PCI–thrombin–heparin
Michaelis complex. (A) The complex is shown with PCI in the
standard orientation with the yellow RCL on top and the red
β-sheet A facing. The P1 Arg residue is shown as yellow rods,
and the heparin binding helix H is at the back of the PCI in
blue. Thrombin is on top, with its light chain colored magenta
and the heavy chain colored cyan. The heparin disaccharide built
into electron density is shown as green rods. (B) The same view
as in A but colored according to temperature factor (B-factor
from blue to red) to illustrate the mobile regions.
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