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Figure 1.
Figure 1. Ribbon Diagrams of ErbB4 Kinase Structures
(A)
The active conformation of the ErbB4 kinase. The activation loop
is colored red.
(B) An inactive conformation of the ErbB4
kinase in complex with lapatinib, which is shown as a red stick
model. The activation loop is disordered, but the loop termini
are colored red.
(C) Superposition of the active and
inactive conformations of the ErbB4 kinase.
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