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Figure 1.
Figure 1. Structures of the Type I IL-4, Type II IL-4, and
Type II IL-13 Ternary Complexes
(A) The type I complex with
IL-4Rα (blue), IL-4 (red), and γ[c] (gold).
(B) The type
II IL-4 complex with IL-4Rα (blue), IL-4 (red), and IL-13Rα1
(green).
(C) The type II IL-13 complex with IL-4Rα (blue),
IL-13 (yellow-orange), and IL-13Rα1 (green).
The complexes
are shown from the side with a cartoon of a membrane underneath
(left), and as viewed from the “top” (right). Glycan
moieties on Asn residues are shown in ball-and-stick
representation. All figures were generated with PyMol (DeLano,
2002).
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