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Figure 1.
Fig. 1. Stereoviews of three conformations of MsbA. (A)
Nucleotide bound. (B) Open apo. (C) Closed apo. One monomer in
each model is colored with a rainbow gradient (N terminus is
blue, C terminus is red), and the other is white. TM helices
(TM1–TM6), extracellular loops (EL1–EL3), and intracellular
helices (IH1–IH2) are labeled accordingly. AMPPNP molecules
are displayed as blue sticks in the nucleotide-bound structure.
In all structures, TM4/TM5/IH2 (yellow and orange) associates
with the opposite monomer in a conserved manner.
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