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Figure 1.
FIGURE 1. The UBA domain of EDD binds to ubiquitin and
polyubiquitin. A, in vitro binding of the EDD and Cbl-b UBA
domains to ubiquitin agarose. B, in vitro binding of the EDD and
Cbl-b UBA domain to ubiquitin chains. C, calorimetric titration
of the EDD UBA domain with ubiquitin. The panel shows the
integrated heat released after correction for the heat of
dilution (data points, squares) and the curve of best fit for
binding to a single site.
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