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Figure 1.
Figure 1. Crystallized TLR-VLR Hybrid Proteins
Full-length and VLR hybrids of TLR1 (A) and TLR2 (B) are
represented schematically. TLR1 and TLR2 and hagfish VLRB.61 are
shown in green, blue, and white boxes, respectively. The
ligand-binding and dimerization domains were identified from our
crystal structure. Amino acid sequences at the fusion boundaries
and the corresponding conserved patterns are given underneath
the boxes. The sequences within the parentheses are non-native
sequences from the cloning sites.
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