Figure 1.
Figure 1. Crystal structure of Fab F-22-30. (a) Final electron
density map (contoured at 1.2 )
of a segment from the H3 hypervariable loop (Ser105H-Trp109H).
(b) Molecular surface of the antibody recombination site. The
positions of some hypervariable loops are indicated. Note a deep
pocket delimited by the L1, L3, and H3 hypervariable loops. (c)
A difference Fourier (F[o] - F[c]) map contoured at 3 suggests
that an unidentified molecule binds to this pocket in the
crystal.
The above figure is reprinted
by permission from John Wiley & Sons, Inc.:
Proteins
(2008,
70,
284-288)
copyright 2008.
)
of a segment from the H3 hypervariable loop (Ser105H-Trp109H).
(b) Molecular surface of the antibody recombination site. The
positions of some hypervariable loops are indicated. Note a deep
pocket delimited by the L1, L3, and H3 hypervariable loops. (c)
A difference Fourier (F[o] - F[c]) map contoured at 3