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Figure 1.
Figure 1: Structures of the substrate complexes. The same
colour scheme is used in all figures. The DNA template,
non-template and RNA strands are in red, blue and yellow,
respectively. The BH, the TH and the rest of the RNAP molecule
are in magenta, cyan and grey, respectively. The insertion and
preinsertion NTP analogues and Stl are designated by green,
orange and black, respectively. The catalytic Mg^2+ ions (MgI
and MgII) are shown as magenta spheres. a, b, Overall views of
the ttEC/AMPcPP (a) and EC/AMPcPP/Stl (b) complexes. CC, coiled
coil. c, d, Superposition of the NTPs (c, d) and TH (d) in the
insertion (green, NTP; cyan, TH) and preinsertion (orange, NTP;
blue, TH) complexes.
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