Figure 1 - full size

 

Figure 1.
(a) Schematic of the five domains of Hel308. Domain boundaries are indicated on top, sequence motifs beneath. Roman numerals, SF2 helicase motifs; , -hairpin loop; R, ratchet helix; RAR, Arg-Ala-Arg motif. (b) Hel308 (ribbon, colored as in a) in complex with the 15-base-pair DNA duplex and 10-base single-stranded 3' tail (beige sticks). (c) Schematic showing key interactions (dashed lines) of Hel308 with the partially unwound DNA substrate.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nat Struct Biol (2007, 14, 647-652) copyright 2007.