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Figure 1.
(a) Schematic of the five domains of Hel308. Domain
boundaries are indicated on top, sequence motifs beneath. Roman
numerals, SF2 helicase motifs; ,
-hairpin
loop; R, ratchet helix; RAR, Arg-Ala-Arg motif. (b) Hel308
(ribbon, colored as in a) in complex with the 15-base-pair DNA
duplex and 10-base single-stranded 3' tail (beige sticks). (c)
Schematic showing key interactions (dashed lines) of Hel308 with
the partially unwound DNA substrate.
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