|
Figure 1.
Figure 1. Re-engineered Variants of Internalin (InlA) in
Complex with the N-Terminal Domain of Human E-Cadherin
(A)
Superposition of InlA/hEC1 (violet) and InlA^S192N-Y369S/hEC1
(gray).
(B) Critical residues near mutation site
S192N[InlA] are shown as ball and stick. Asn192[InlA] adds a
direct H bond to the carbonyl oxygen of Phe17[hEC1].
(C)
The mutation Y369S[InlA] introduces a water-bridged interaction
to Asn27[hEC1].
|
