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Figure 1.
Fig. 1. The structure of the NTD of human Nup214. (A)
Domain structure of Nup214 and Nup159. The construct used for
crystallization is boxed red, and two phosphorylation sites of
the NTD are indicated. Residues observed in the crystal
structures are boxed in blue. (B) Schematic representation of
the NTD structure. The blades of the  -propeller are labeled
from 1 to 7. The CTE is shown in blue, and -strands forming the
double-Velcro closure are indicated with an asterisk. (C) Ribbon
representation of the NTD structure. A 180°-rotated view is
shown on the right. As a reference, the strands of blade 3 are
labeled A–D. The blades of the -propeller and the CTE
are labeled as in B. The helical insertions are shown in pink.
(D) Ribbon representation of side views of the structure of the
NTD. The view on the right is rotated by 180°.
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