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Figure 1.
Figure 1 Homotrimeric structure of the recognition domains of
human L- and H-ficolins and location of their binding site(s).
(A, B) L-ficolin structure seen from the target binding surface
(bottom view) and on a perpendicular side view. (C, D)
Corresponding bottom and side views of the H-ficolin structure.
The side chains of the binding site residues are displayed as
ball and sticks and colored green (S1), red (S2), black (S3),
and orange (S4). To enhance clarity of the side view, only one
of each representative binding sites is shown on the L-ficolin
trimer. N and C indicate the N- and C-terminal ends of each
protomer. Ca^2+ ions are represented as golden spheres. Figure
generated using MOLSCRIPT (Kraulis, 1991).
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