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Figure 1.
Fig. 1. Ribbon diagrams of the rASPA monomer and dimer. (A)
N-domain of rASPA is color-coded in cyan and red. C-domain is
color-coded in yellow and green. Residues His-21, Gly-22,
Glu-24, Asn-54, Arg-63, Asn-70, Arg-71, Phe-73, Asp-114,
His-116, and Glu-178 (blue sticks) are highly conserved in the
AstE-AspA family and delineate the active site. Zn^2+ is shown
as a pink sphere. (B) The rASPA dimer observed in the asymmetric
unit of the rASPA crystals is shown in ribbon representation.
Both the N-domain (red) and C-domain (green) of the rASPA
monomers are involved in formation of the dimer interface.
Residues His-21, Glu-24, and His-116 (blue sticks) coordinate
Zn^2+ (pink sphere).
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