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Figure 1.
Fig. 1. Structures of B[c]Ph, its B[c]Ph DE metabolite, and
the 1S adduct derived from trans-opening of this epoxide by the
exocyclic 2-amino group of deoxyguanosine. The tetrahydrobenzo
ring numbering system and the absolute configuration
designations for the diastereomer used in the present study are
shown. Note that the absolute configuration at C1 of the epoxide
inverts upon trans-adduct formation.
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