Figure 1 - full size

Figure 1. Fig. 1. Simulated annealing omit electron density maps contoured at 3.5 showing bound inhibitors, waters and mutated residues within one of the HIV-1 RT subunits as indicated. (A) Lys101Glu in p66 and nevirapine. (B) Glu138Lys in p51 and nevirapine. (C) Glu138Lys in p51 and PETT-2.

The above figure is reprinted by permission from the Federation of European Biochemical Societies: FEBS J (2006, 273, 3850-3860) copyright 2006.