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Figure 1.
Figure 1. Crystal structure of TM1553. A: Ribbon drawing where
the N-terminal domain (cyan), helical domain (pink), linker
region (slate-blue), and C-terminal domain (yellow) are colored
to illustrate the domain organization. Helices (H1-H12) and  -strands
( 1-
15)
are labeled, and the unknown ligand is represented as orange
spheres. B: Diagram showing the secondary structural elements in
TM1553 superimposed on its primary sequence. The  -helices,
3[10]-helices, -strands
(indicated by red A, B, C, and D to represent the -sheet
designation), -bulges,
and  -turns
are indicated. The -hairpins
are depicted as red loops. Dashed lines indicate that no
electron density was observed for that region.
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