Figure 1 - full size

 

Figure 1.
Fig. 1. Catalytic reaction of HO. (A) Enzymatic cycle of heme metabolism to biliverdin catalyzed by HO. The reactions shaded in blue indicate the ET step from CPR to heme to be used for the reduction of Fe^III(Schiff-base) complexes. (B) Chemical structures of heme (Left) and Fe^III(Schiff-base) (Right).