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Figure 1.
Fig. 1. Fus3 recruitment to the pheromone response MAPK
complex. (A) Schematic of pheromone response MAPK complex. The
MAPK Fus3 interacts with the scaffold protein Ste5 (4–6) and
the MAPKK Ste7 (6, 40). (B) Maps of the interaction domains in
the MAPKK Ste7 and the scaffold Ste5. Minimal Fus3 binding
peptides are shown in color [dark blue, Ste7_pep1 (12, 16);
light blue, Ste7_pep2 (16)]. Black bars above the Ste5 schematic
indicate protein-interaction domains identified in yeast
two-hybrid assays (4, 37). The Fus3 binding peptide (Ste5_pep)
is shown in red (fig. S1).
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