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Figure 1.
Figure 1. The Overall Structure of Murine Coronin-1
(A) Ribbon diagrams of coronin-1 showing the "top" (left) and
"bottom" (right) side of the b propeller. The structure can be
divided into an N-terminal seven-bladed b propeller (residues
8-352; colored blue, yellow, and green) and a C-terminal
extension (residues 353-402; colored red). The last ordered
residues of the N and C termini are marked with an "NT" and
"CT," respectively. The individual blades are numbered from one
to seven; the strands in each blade are named A-D and are
labeled in blade 4.
(B) The "side" view highlights the
C-terminal extension (red) tightly packing against the "bottom"
surface of the propeller. The structure lacks the C-terminal
leucine zipper responsible for multimerization (Gatfield et al.,
2005 and Oku et al., 2005), and, accordingly, the protein is
monomeric. All figures were generated with PyMol (DeLano, 2002).
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