Figure 1.
Figure 1. Views of Pvs25. (a) The triangular prism formed by
domain 1 (light blue), domain 2 (green), domain 3 (red) and
domain 4 (gold). The central -strands
in each domain are labeled 1 and 2. The 11 disulfide bonds
(violet) are shown. (b) View of the edge of the prism. (c) Pvs25
forms sheets in the crystals. One molecule (red) makes contacts
with four 2[1] symmetry mates (light blue) and two molecules
related by lattice translations (dark blue). The six light blue
molecules all have the same triangular face 'up', whereas the
other three molecules (red and dark blue) all have the opposite
face 'up'. As P25 and P28 molecules are thin prisms, the
glycosylphosphatidylinositol anchor could reach the cell
membrane whether a molecule was facing 'up' or 'down' on the
membrane. N term, N terminus; C term, C terminus.
The above figure is reprinted
by permission from Macmillan Publishers Ltd:
Nat Struct Mol Biol
(2006,
13,
90-91)
copyright 2006.
-strands
in each domain are labeled 1 and 2. The 11 disulfide bonds
(violet) are shown. (b) View of the edge of the prism. (c) Pvs25
forms sheets in the crystals. One molecule (red) makes contacts
with four 2[1] symmetry mates (light blue) and two molecules
related by lattice translations (dark blue). The six light blue
molecules all have the same triangular face 'up', whereas the
other three molecules (red and dark blue) all have the opposite
face 'up'. As P25 and P28 molecules are thin prisms, the
glycosylphosphatidylinositol anchor could reach the cell
membrane whether a molecule was facing 'up' or 'down' on the
membrane. N term, N terminus; C term, C terminus.