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Figure 1.
Figure 1. Overall structure of KOD DNA polymerase. The
structure is composed of domains and subdomains, namely the
N-terminal domain (N-ter, violet), exonuclease domain (Exo,
gray) including the unique loop (blue), polymerase domain (Pol)
including the Palm (brown) and Fingers (green) subdomains, and
the Thumb domain (red), including the Thumb-1 and Thumb-2
subdomains and disordered regions (dotted lines). The orange
region represents the E-cleft. The positions of two amino acids
in the exonuclease domain are shown as colored balls (red,
AA147; light blue, AA142).
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