|
Figure 1.
Figure 1: Fosfomycin biosynthesis. The fosfomycin
biosynthetic pathway requires phosphoenolpyruvate mutase (Fom1),
phosphonopyruvate decarboxylase (Fom2), phosphonoacetaldehyde
methyltransferase (Fom3) and HppE (Fom4). 1, phosphoenolpyruvate
(PEP); 2, phosphonopyruvate (PnPy); 3, phosphonoacetaldehyde
(PnAA); 4, (S)-2-hydroxypropylphosphonic acid (S-HPP); 5,
fosfomycin. C1 and C2 positions are shown in blue.
|
