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Figure 1.
Figure 1. Crystal structure of mRNA decapping enzyme (DcpS)
from Mouse. (A) Stereo ribbon diagram of Mouse DcpS color-coded
from N-terminus (blue) to C-terminus (red) showing the domain
organization with helices H1-H13 and -strands
1-
14,
as well as -sheets
A, B, C, and D. (B) Diagram showing the secondary structure
elements in Mouse DcpS (chain A) superimposed on its primary
sequence. The -sheet
strands are indicated by a red A, B, C, and D. -bulges
and -turns
are indicated. -hairpins
are depicted as red loops. Disordered regions are depicted by a
dashed line with the corresponding sequence in brackets. The HIT
sequence motif is indicated by a black line above the three
histidines.
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