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Figure 1.
Fig. 1. Overview of X. tropicalis Spred1 EVH1 domain
structure. (a) Cartoon of secondary structure. Helices are shown
as rectangles, β-strands as arrows. Structure is shown with the
front sheet of the β-sandwich rotated about a hinge at the top
of the sandwich, represented by the dotted grey line. The front
sheet is shown in light grey, the back sheet in dark grey. The
β4–β5 loop is broken to rotate the top sheet, and is shown
by broken line. (b) Comparison of the two molecules observed in
the asymmetric unit. Structures are shown in the cartoon
representation. The lower view is rotated by 180° about the
vertical axis. Dark grey: molecule A; light grey: molecule B.
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