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Figure 1.
Figure 1. Structure of mCAR LBD/Androstenol Complex(A and
B) Ribbon representation of each CAR molecule within the
asymmetric unit. The arrow indicates the region of missing
density between helices H11 and H12 in molecule B. The bound
ligand is also displayed in each molecule as ball-and-stick
representations.(C) F[o]-F[c] omit map contoured at 5σ for
androstenol within the binding pocket. The model is superimposed
on the electron density, and the androstenol is colored blue
(carbon) and red (hydroxyl).(D) Electrostatic surface
representation of the ligand binding pocket. Androstenol is
shown in black (carbon) and red (hydroxyl).
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