Figure 1.
Figure 1. Superimposition of the Pol structures.
(a) The C traces
of the binary (dark gray), nick ternary (green) and precatalytic
ternary (orange) structures reveal two differences. One involves
-strand
8 (ref. 10) (labeled A). The second involves -strands
3 and 4 (B; see text). Black lines indicate the span of the
different subdomains: 8 kDa domain (8), fingers (F), palm (P)
and thumb (T). (b) DNA shift upon dNTP binding. The DNA and part
of the palm subdomain is shown for the binary (blue) and
precatalytic ternary complex (yellow-brown). Hydrogen bonds,
dashed lines; Mg2+ ion observed in the structure of the ternary
complex, green.
The above figure is reprinted
by permission from Macmillan Publishers Ltd:
Nat Struct Mol Biol
(2005,
12,
97-98)
copyright 2005.
structures.
(a) The C 
traces
of the binary (dark gray), nick ternary (green) and precatalytic
ternary (orange) structures reveal two differences. One involves
-strand
8 (ref. 10) (labeled A). The second involves