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Figure 1.
FIG. 1. Pim-1 adopts a typical kinase fold. a, ribbon
diagram of apo Pim-1 kinase crystal structure produced using
Ribbons (35). The secondary structure  -helix and  -strand
are labeled following the conventions of the literature. The
H1-
and H2-strands are unique to
Pim-1 kinase structure and are so named for their helical
structure in cAPK. The shaded area represents the ATP binding
pocket with the active site residues shown and labeled with
single letter amino acid abbreviations and position numbers. b,
an overlay of Pim-1 and PhK using catalytic loops (produced
using Quanta). The active site residues that bind or catalyze
ATP were shown and and labeled (with single letter amino acid
abbreviations and position numbers) on the C trace of selected
regions.
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