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Figure 1.
Figure 1 Crystal structure of ANK complexed with 2-5A. (A)
Structural and functional domains of RNase L. Ankyrin repeats
are shown starting with blue at repeat 1 and ending with red at
repeat 8. (B) Structure of the predominant trimeric species of
2-5A ((pp)p(A2'p5')[2]A) (Kerr and Brown, 1978). (C, D) Surface
(top) and ribbon (bottom) representations of the ANK/2-5A
complex. Ankyrin repeats (R1 -R8) are shown as in (A). The bound
2-5A molecule is shown as a ball-and-stick model. The view in
(D) was obtained by rotating the view in (C) by 90°.
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