Figure 1.
Figure 1: Modes of base pairing for 8oxoG. a, Oxidation of
guanine at C8 by reactive oxygen species (ROS). b, 8oxoG in a
Watson-Crick base pair with dC. Dashed lines indicate potential
hydrogen bonds. c, 8oxoG (syn) in a Hoogsteen base pair with dA
(anti).
The above figure is reprinted
by permission from Macmillan Publishers Ltd:
Nature
(2004,
431,
217-221)
copyright 2004.
