Figure 1 - full size

 

Figure 1.
Figure 1: Structure of the PA -CMG2 complex. Two orthogonal views are shown in ribbon representation. PA is coloured by domain (I -IV). CMG2 is blue; the metal ion is shown as a magenta ball. PA domain I is cleaved after receptor binding, leading to the loss of domain Ia (yellow) and the formation of PA[63]. All molecular graphics images were generated using the UCSF Chimera package^29 (http://www.cgl.ucsf.edu/chimera).

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nature (2004, 430, 905-908) copyright 2004.