Figure 1 - full size

 

Figure 1.
Figure 1 Oligonucleotide sequences and DNA adducts. (A) The 14 nt primers are identical in all trials and terminated by ddC (indicated by C^*). Template strands are 18 nt long with a 3'-dG overhang. X denotes the position of the lesion for primer/template combinations (1) and (2), and the arrow the position of dNTP incorporation. (B) Structures of the lesions at position X in the templates 8-oxodG and tetrahydrofuran (abasic site model).

The above figure is reprinted from an Open Access publication published by Macmillan Publishers Ltd: EMBO J (2004, 23, 1494-1505) copyright 2004.