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Figure 2.
Figure 2. Close-Up Views of the Abasic Lesion in the Ab-1
(A), Ab-2A (B), and Ab-3 (C) ComplexesThese structures represent
the likely events when Dpo4 encounters an abasic lesion. Three
base pairs including the incoming nucleotide and two metal ions
are shown as ball-and-stick models and superimposed with a final
refined 2F[o] − F[c] electron density map contoured at 1.0 σ
(gray). The template strand is shown in yellow with the abasic
site highlighted in green, the primer strand in pink, the
incoming nucleotide in purple, and the divalent cations in
orange.
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