Figure 1 - full size

 

Figure 1.
FIG. 1. a, domain structure of the p62 protein and Paget's disease of bone mutation sites (SH2, AID, ZZ, and TRAF6 refer to binding sites for the SH2 domain of p56^lck, aPKC, RIP, and TRAF6, respectively), and b, sequence alignment of the p62-UBA domain with the HHR23A-UBA domains (alignment from SMART data base; see Ref. 7).

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2003, 278, 37409-37412) copyright 2003.