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Figure 2.
Figure 2. Structure of Human Magoh(A) Alignment of a
diverse subset of known Magoh sequences. The shaded regions
indicate ≥80% sequence identity. Secondary structure
assignments are shown above the alignments, and residues
contacting Y14 (< 3.8 Å) are marked with an asterisk. Hs,
human; Dm, D. melanogaster; Ce, C. elegans; At, A. thaliana; Sp,
S. pombe.(B) A ribbon diagram of Magoh as seen bound to Y14.(C)
σ[A]-weighted 2Fo-Fc electron density for the refined structure
at 2 Å resolution, contoured at 1.4 σ. The orientation of
the indicated β strands is the same as that shown in (B).The
molecular drawings in Figure 2, Figure 3, Figure 4, Figure 5 and
Figure 6 were prepared with PYMOL [46].
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