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Figure 1.
Figure 1. (A) ApoA and ApoB superimposed. The two molecules
in the asymmetric unit are superimposed to show that they differ
in overall domain rotation. ApoA is black and ApoB is gold.
Broken lines are distances of representative areas of the small
lobe. The distance between the Ser53 C^a atoms, in the Gly-rich
loop, is 1.9 Å. The distance between the C^a atoms of
Ser339 is 3.4 Å. An MPD molecule and a covalently attached
b-ME group were seen in both structures. The ApoA MPD and b-ME
modified Cys199 are pink. Residues 128-300 were superimposed.
(B) The F[o] -F[c] omit map of Cys199 and the covalently
attached b-ME, contoured at 3s. Oxygen, red; nitrogen, blue;
carbon, gray; sulfur, green.
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