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Figure 1.
Figure 1. Ribbon diagram of the IMPDH tetramer viewed along
the 4-fold axis. Each monomer displays the enzyme in one of the
complexes presented here. At the top left, IMP is shown in green
and at bottom left, the IMP-MPA complex is shown with MPA
(orange). At the top right, the XMP-MPA complex is shown with
XMP (blue). At the bottom right, the enzyme is in complex with
XMP and the cofactor NAD^+ (yellow). Although the cofactor lies
along the dimer interface, it does not make contact with the
neighboring monomer. All molecular images were prepared with the
program Deepview 3.7[37.] and rendered in POVRAY 3.5 beta
(www.povray.org).
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