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Figure 1.
Figure 1. Sequence(A) Schemata of Xenopus Dsh (XDsh) and
Dpr (XDpr) showing conserved domains DIX, PDZ, and DEP, and
leucine zipper (LZ) and PDZ binding (PDZ-B) domains,
respectively. Gray in XDsh indicates yeast two-hybrid bait.
Vertical arrows indicate the positions of XDsh mutations
discussed in the text. The horizontal arrow indicates the 5′
extent of XDpr clone obtained from the screen.(B) Alignment of
XDpr (X) with orthologs from mouse (M) and human (H). Black
residues are identical; gray residues are conserved; horizontal
arrow as in (A).
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