Figure 1 - full size

 

Figure 1.
Figure 1: Overall structure of the Cul1-Rbx1-Skp1-F boxSkp2 quaternary complex. Cul1, Rbx1, Skp1 and the F-box of Skp2 are coloured in green, red, blue and magenta, respectively. The five helices that make up the cullin-repeat motif are labelled for the second repeat. Figures were prepared with the programs MOLSCRIPT49, GL_RENDER and POVRAY (L. Essar, personal communication).

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nature (2002, 416, 703-709) copyright 2002.