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Figure 1.
Figure 1. Three-Dimensional Structure of the Synaptotagmin 1
C2B-Domain. (A) and (B) show superpositions of the 20
structures with the lowest NOE energies in two different
orientations. (C) and (D) are ribbon diagrams of the structure
of the C2B-domain in the same orientations. Strands are labeled
from 1 to 8, helices are labeled HA and HB, and the Ca2+ ions
(orange spheres) are labeled Ca1 and Ca2. Note that the loop
connecting strands 5 and 6 forms a very short alpha-helix in some
C2-domains but such helix is not observed in the structure of
the synaptotagmin 1 C2B-domain. The figure was generated with
the programs InsightII (MSI, San Diego, California) and
Molscript (Kraulis, 1991).
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