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Figure 1.
Fig. 1. Oligosaccharide structures. (A) The pentasaccharide
co-crystallized with both DC-SIGN and DC-SIGNR. Residue numbers
used in the text are shown in parentheses. (B) N-linked
high-mannose structure. The full nine-mannose structure (Man[9])
is shown, but the presence of  1-2 linked
mannose at the branch termini is variable. The inner branched
trimannose structure Man 1-3 [Man
1-6]Man is
shown in the red box, and the outer trimannose structure is
shown in the yellow box. (C) Typical N-linked complex
carbohydrate. The portion equivalent to the pentasaccharide used
in this study is boxed in red. The inner trimannose structure is
common to both complex and high-mannose N-linked
oligosaccharides. Gal, galactose; GlcNAc, N-acetylglucosamine;
Man, mannose; Sia, sialic acid.
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