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Figure 1.
Fig. 1. Atomic structure of bovine Arp2/3 complex viewed from
the front. This standard view shows Arp2 in the classic actin
orientation. (A) Stereopair of ribbon diagrams (40-42). Color
codes for subunits: Arp3, orange; Arp2, red for subdomains 3 and
4, gray-red for the actin backbone model of subdomains 1 and 2;
p40, green; p34, light blue; p20, dark blue; p21, magenta; p16,
yellow. (B) Space-filling model with the subdomains of Arp2 and
Arp3 indicated (43). (C) Space-filling model with the
electrostatic potential indicated with blue as positive and red
as negative (43). Both p21 and p40 have strongly basic surface
patches. The actin backbone model of Arp2 subdomains 1 and 2 is
outlined in (B) and (C).
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