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Figure 1.
Figure 1. Ribbon plot of cdMMP-12 (yellow) displayed in
standard orientation. The cdMMP-12 ribbon shown together with
the bound batimastat inhibitor in the normal conformation, is
superimposed with the catalytic domains of MMP-1 (red, PDB
accession code 966C), MMP-2 (dark blue, lacking the fibronectin
type II domains for clarity, 1QIB), MMP-3 (green, 1CAQ), MMP-7
(dark orange, 1MMQ), MMP-8 (gray, 1MMB), MMP-12 (yellow), MMP-13
(light blue, 830C) and MMP-14 (violet red, 1BQQ). The catalytic
and the structural zinc ion and the three bound calcium ions are
displayed as pink and blue spheres, respectively, and the three
His residues liganding the catalytic zinc and the characteristic
Met236 are shown with all non-hydrogen atoms. The Figure was
made with BOBSCRIPT[55] and Raster3D. [56]
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