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Figure 1.
Fig. 1. Electron density in the site III interface of the
vIL-6-gp130 complex. Viral IL-6 is in yellow and the gp130 D1
domain is in red. At the center of the map is vIL-6 Trp144,
which is at the core of the site III interface. The -sheet
strands of the gp130 D1 (F and G strands) are labeled in red.
The electron density map is a SIGMAA-weighted 2F[obs] - F[calc]
map at 2.4 Å contoured at 1.2 and
displayed with the program O (45).
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