Figure 1 - full size

 

Figure 1.
Fig. 1. Electron density in the site III interface of the vIL-6-gp130 complex. Viral IL-6 is in yellow and the gp130 D1 domain is in red. At the center of the map is vIL-6 Trp144, which is at the core of the site III interface. The -sheet strands of the gp130 D1 (F and G strands) are labeled in red. The electron density map is a SIGMAA-weighted 2F[obs] - F[calc] map at 2.4 Å contoured at 1.2 and displayed with the program O (45).

The above figure is reprinted by permission from the AAAs: Science (2001, 291, 2150-2155) copyright 2001.