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Figure 1.
Fig. 1. Schematic diagram of the HRSV F protein sequence.
F1 and F2 are formed after proteolytic cleavage of the precursor
F0. The signal peptide (SP), the cleavage site (CS), the
putative fusion peptide (FP), the N-terminal HR (HR-N) region,
the C-terminal HR (HR-C) region, and the transmembrane segment
(TM) within the amino acid sequence of the recombinant recRSV-1
construct are indicated. The HR-N and HR-C regions predicted by
LEARNCOIL-VMF are represented by shaded boxes.
Protease-resistant fragments from trypsin (HRSV-N57 and
HRSV-C45) and proteinase K (HRSV-N51 and HRSV-C39) cleavage are
indicated.
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