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Figure 1.
Figure 1: Structure of the Skp1-Skp2 complex. Skp1 is shown
in blue and Skp2 is shown in red. The boundaries of the BTB/POZ
fold, the C-terminal helical extension of Skp1 and of the F-box,
the three non-canonical LRRs, the seven canonical LRRs and the
C-terminal tail of Skp2 are shown in the diagram below the
structure. The 100-residue N-terminal Skp2 region missing from
the crystallized protein is indicated (dashed line). The second
LRR has a partially disordered loop instead of the helix
characteristic of LRRs.
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