Figure 1 - full size

 

Figure 1.
Fig. 1. Structure of the carboxyl-terminal domain of eIF4A. (A) Stereoview, ribbon drawing of the structure. Conserved motifs are colored as follows: motif IV, VIFCNTRR, residues 263-270, green; "conserved R" motif, residue Arg-298, purple; motif V, RGID, residues 321-324, magenta; motif VI, HRIGRGGR, residues 345-352, cyan. The strands of the -sheet are labeled sequentially. This and subsequent ribbon drawings were prepared with MOLSCRIPT (34) and rendered with RASTER3D (35). (B) Topology diagram of the structure. -Strands are shown as arrows; -helices, as cylinders. -Strands and -helices are labeled sequentially as 1-7 and [1]- [6], respectively. Sequences of the conserved motifs are shown in boxes; residues whose side chains are illustrated in A and subsequent figures are underlined.