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Figure 1.
Fig. 1. Structure of the carboxyl-terminal domain of
eIF4A. (A) Stereoview, ribbon drawing of the structure.
Conserved motifs are colored as follows: motif IV, VIFCNTRR,
residues 263-270, green; "conserved R" motif, residue Arg-298,
purple; motif V, RGID, residues 321-324, magenta; motif VI,
HRIGRGGR, residues 345-352, cyan. The strands of the -sheet are
labeled sequentially. This and subsequent ribbon drawings were
prepared with MOLSCRIPT (34) and rendered with RASTER3D (35).
(B) Topology diagram of the structure. -Strands are
shown as arrows; -helices,
as cylinders. -Strands and
-helices
are labeled sequentially as 1-7 and [1]- [6],
respectively. Sequences of the conserved motifs are shown in
boxes; residues whose side chains are illustrated in A and
subsequent figures are underlined.
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